Confused about MTHFR?

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Practitioners Worldwide.

Understand MTHFR, methylation and patient health. An evidence-based, straightforward clinical guide.

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The MTHFR gene is one of the most commonly discussed (and misunderstood) genetic markers in integrative and functional medicine. If you’ve ever felt unsure about how to interpret MTHFR test results or what they actually mean for your patients, this guide is for you.

What You’ll Get:


A 16-page evidence-based guide including:

  • What MTHFR is and why it matters in clinical practice

  • The functional impact of C677T,  A1298C SNPs and compound heterozygosity

  • Where MTHFR sits in the methylation pathway

  • Overview of methylation and why it matters

  • How MTHFR activity affects homocysteine, methylation and health

  • Clinical signs and environmental factors that influence methylation

  • Next steps to integrate DNA testing into practice

Who is this for?


Whether you're a naturopath, dietician, nutritionist, integrative GP, functional medicine practitioner, pharmacist, osteopath or other allied health practitioner, this guide will help you better understand your patients' genetics and understand how this gene influences methylation and health.

Meet
Dr. Denise Furness (PhD)


Dr. Denise Furness is a geneticist, researcher, and functional medicine expert with over 20 years of experience in nutrigenomics, methylation, and epigenetics. She specialises in helping health professionals apply DNA insights in clinical practice to improve patient outcomes—from preconception care and fertility to healthy aging and the prevention of age-related conditions.

 

Denise is passionate about helping people work with their genes—not against them—and supporting practitioners to bridge the gap between complex genetic science and real-world healthcare. Her mission is to empower health professionals to deliver personalised, preventative care with clarity and confidence.

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